Which of the following signs can indicate a risk of depression in patients?

Apathy and indifference are significant indicators of depression. These symptoms reflect a lack of interest or concern in activities that typically engage a person, as well as a decreased emotional response to situations that would normally elicit feelings of joy or sadness. In the context of depression, individuals often withdraw from social interactions and show minimal motivation to participate in their daily lives. This emotional numbness and disinterest can be critical indicators for healthcare providers when assessing a patient's mental health and potential risk for depression.

In contrast, engagement in activities and consistent attendance in therapy are generally signs of positive mental health or active efforts to address mental health issues. Positive alterations in memory could suggest cognitive improvement rather than an indicator of depressive symptoms, making them less relevant when considering signs of depression.